Published on December 10, 2019
It has long been recognized that solid tumors contain poorly vascularized regions characterized by severe hypoxia (oxygen deprivation), acidosis and nutrient starvation.[1] Over the past decade, work from many laboratories has indicated that hypoxic micro-environments contribute to cancer progression by activating adaptive transcriptional programs that promote cell survival, motility and tumor angiogenesis.[2]
Oxygen pulls the rug out from under cancer cells and tumors by removing the basic condition that makes them virulent. Bicarbonates do the same thing so using oxygen and bicarbonate together is lethal to cancer cells. (Low Oxygen Causes Infections, which Cause Cancer & The Key Cause of Cancer is Oxygen Deficiency)
Northeastern University researchers have found that inhaling supplemental oxygen—40 to 60% oxygen as opposed to the 21% oxygen in air—can weaken immunosuppression and awaken anti-tumor cells. The new approach, some 30 years in the making, could dramatically increase the survival rate of patients with cancer, which kills some 8 million people each year. The break through findings were published in Science Translational Medicine.
Dr. Michail Sitkovsky, an immune physiology researcher at Northeastern found that supplemental oxygenation inhibits the hypoxia-driven accumulation of adenosine in the tumor micro-environment and weakens immunosuppression. This, in turn, could improve cancer immunotherapy and shrink tumors by unleashing anti-tumor T lymphocytes and natural killer cells.
“Breathing supplemental oxygen opens up the gates of the tumor fortress and wakes up ‘sleepy’ anti-tumor cells, enabling these soldiers to enter the fortress and destroy it,” explained Sitkovsky, the Eleanor W. Black Chair and Professor of Immunophysiology and Pharmaceutical Biotechnology in the Bouvé College of Health Sciences’ Department of Pharmacetical Sciences.
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Sitkovsky and colleagues looked at one particular property of tumors. They can live without much oxygen, in what are known as hypoxic environments. “Since the root of all problems is the lack of oxygen in tumors, a simple solution is to give tumors more oxygen,” Sitkovsky told NBC News.
It has long been recognized that solid tumors contain poorly vascularized regions characterized by severe hypoxia (oxygen deprivation), acidosis and nutrient starvation.[1] Over the past decade, work from many laboratories has indicated that hypoxic micro-environments contribute to cancer progression by activating adaptive transcriptional programs that promote cell survival, motility and tumor angiogenesis.[2]
Oxygen pulls the rug out from under cancer cells and tumors by removing the basic condition that makes them virulent. Bicarbonates do the same thing so using oxygen and bicarbonate together is lethal to cancer cells. (Low Oxygen Causes Infections, which Cause Cancer & The Key Cause of Cancer is Oxygen Deficiency)
Any element that threatens the oxygen carrying capacity
of the human body will promote cancer growth.
Dr. Michail Sitkovsky, an immune physiology researcher at Northeastern found that supplemental oxygenation inhibits the hypoxia-driven accumulation of adenosine in the tumor micro-environment and weakens immunosuppression. This, in turn, could improve cancer immunotherapy and shrink tumors by unleashing anti-tumor T lymphocytes and natural killer cells.
Accumulated acid residues at the
cellular level drown out Oxygen.
“Breathing supplemental oxygen opens up the gates of the tumor fortress and wakes up ‘sleepy’ anti-tumor cells, enabling these soldiers to enter the fortress and destroy it,” explained Sitkovsky, the Eleanor W. Black Chair and Professor of Immunophysiology and Pharmaceutical Biotechnology in the Bouvé College of Health Sciences’ Department of Pharmacetical Sciences.
Want to understand your health situation and learn what best to do to feel better? Schedule a free 15-minute Exploratory Call with Dr. Sircus »
Sitkovsky and colleagues looked at one particular property of tumors. They can live without much oxygen, in what are known as hypoxic environments. “Since the root of all problems is the lack of oxygen in tumors, a simple solution is to give tumors more oxygen,” Sitkovsky told NBC News.
Cancer Cells are Easier to Kill
when Oxygen Levels are Increased.